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KMID : 0356920100580040409
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Korean Journal of Anesthesiology
2010 Volume.58 No. 4 p.409 ~ p.412
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Total intravenous anesthesia with propofol and remifentanil in a patient with MELAS syndrome -A case report-
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Park Jin-Suk
Baek Chong-Wha
Kang Hyun
Cha Su-Man
Park Jung-Won
Jung Yong-Hun
Woo Young-Cheol
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Abstract
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A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.
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KEYWORD
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Atracurium, General anesthesia, MELAS syndrome, Propofol, Remifentanil, TIVA
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